What Is THC-P? Understanding This Unique Cannabinoid

What Is THC-P? Understanding This Unique Cannabinoid

As the legal cannabis industry continues to grow, you may have noticed more novel cannabinoids entering the marketplace. Recent research has identified over 120 cannabinoids, including delta 8 and delta 10 THC. One of the latest is THCP, a rare propyl analog of delta-9 THC, noted for its significantly stronger effects compared to delta-9 THC. In this article, you will gain an introductory understanding of this unique cannabinoid - what it is, how it differs from other THC variants, its potential therapeutic effects and side effects, and the current state of research. With cannabis chemistry advancing rapidly, it is important to stay informed on emerging compounds like THCP.

What is THCP?

Tetrahydrocannabiphorol (THCP) naturally occurs in cannabis, though only in trace amounts less than 0.1%. In contrast, THC is typically present at approximately 30%. Despite low concentrations, emerging research suggests THCP may be considerably more potent.

Italian scientists first identified THCP in 2019, meaning the understanding of its potential therapeutic benefits remains relatively limited. 

How THC-P Differs From Other Cannabinoids

THCP differs structurally from THC through longer alkyl side chains. This allows for easier binding throughout the body's receptors. THCP may offer comparable medical benefits to THC, such as pain relief, nausea reduction, and aiding certain disorders.

Further research is still needed, but initial evidence suggests THCP can induce psychoactive effects. It binds more effectively to CB1 receptors than THC, around 33 times stronger. Since psychoactivity stems from THC attaching to these receptors, THCP may produce a sensation over 30 times more potent than THC. Both scientists and consumers note THCP's impacts resemble THC but with significantly higher potency. Careful dosing is advised to avoid potential anxiety or other side effects. 

The Unique Benefits and Effects of THC-P

Pain Relief

THCP shows promise for relieving pain, especially chronic pain conditions that are resistant to other treatments. Studies on mice have found THCP activates the CB1 receptors in the endocannabinoid system, which are involved in pain modulation. THCP appears to have a stronger binding affinity for CB1 receptors than regular THC, which could make it more effective for stubborn pain. For those seeking alternative pain management options, THCP may be worth exploring.

Reduced Side Effects

Another benefit of THCP is that it may produce fewer undesirable side effects than regular THC, such as paranoia or anxiety. Although THCP is still psychoactive, some studies show it leads to a different experiential effect that is perceived as more clear-headed. The reason for this is not fully understood but may have to do with THCP's selectivity for CB1 receptors in the central nervous system. If this finding is confirmed in human studies, THCP could provide therapeutic benefits with fewer side effects for some.

Enhanced Relaxation

Anecdotally, many people report THCP promotes deep relaxation and calmness. At higher doses, THCP may induce drowsiness and even sleep. For those struggling with insomnia or looking to unwind in the evening, THCP could be an appealing option. However, more research is needed to determine the effects of THCP on sleep architecture and restfulness. As with any cannabis product, moderation and cautious experimentation are advised.

In summary, THCP demonstrates some promising and potentially unique effects that set it apart from regular THC. However, cannabis research is still in its infancy, and many questions remain unanswered about this interesting cannabinoid. As scientific inquiry continues, THCP may emerge as an exciting new option for therapeutic use or recreational enjoyment.

Is THC-P Legal?

THCP is completely federally legal and available in most states. Under the 2018 Farm Bill, hemp-derived cannabinoids and products are lawful if THC levels do not surpass 0.3%. Thus, THCP is currently legal at the federal level. However, definitions of "THC" vary between states, so local regulations should be reviewed.

FAQs: Answering Common Questions About THC-P

What is THC-P?

THCP is a cannabinoid that is present in certain cannabis plants. THCP has a stronger affinity for the CB1 receptor than THC, indicating it has stronger psychoactive effects. It is a propyl analog of delta-9 THC, meaning it has an extra carbon atom attached, giving it a slightly different molecular structure. While THCP shares some similarities with delta-9 THC, the primary psychoactive compound in cannabis, THCP is considered to be more potent.

How does THC-P differ from regular THC?

Although THCP and delta-9 THC are very closely related, THCP is estimated to be 33 times more potent than delta-9. This means much smaller amounts of THCP are needed to produce effects. THCP also has a slower onset and longer duration of effects. Some users report THCP produces a more relaxing, sedative high compared to delta-9 THC. However, more research is still needed to fully understand the differences.

What are the effects of THC-P?

The effects of THCP are largely similar to delta-9 THC and include euphoria, relaxation, altered sensory perception, and increased appetite. However, the potency of THCP means these effects may be felt more strongly and last longer. As with delta-9 THC, higher doses of THCP can also induce drowsiness, confusion, and impaired memory. The long term effects of THCP are still unknown and require further study.


A deeper understanding of THCP and other minor cannabinoids could open doors to new therapeutic uses of cannabis. As research continues and public opinion shifts, we may see a future where these compounds are more widely studied, accepted, and available. For now, it’s important to stay informed on the latest science and legal landscape. Approach new cannabinoids with an open mindset. While anecdotal evidence can be enlightening, validated research is key to separating fact from fiction. There is still much to learn about optimizing and harnessing the full potential of cannabis. Keep seeking credible information and thinking critically so you can make the most informed decisions for your health and wellbeing.


Back to blog